Statistical Evaluation of Diagnostic Tests

February 17, 2021

Statistical Evaluation of Diagnostic Tests
Presented by Thomas C. King, MD, PhD, Medical Director
Published February 17, 2021

Dr Tom King, Medical Director at Immunovia, presents the statistical evaluation of diagnostic tests for the early detection of pancreatic cancer.

0:00 Introduction
0:13 Evaluation of diagnostic aids for the early detection of cancer
0:37 Definition of accuracy
1:26 Examples: Pap smears and Serum PSA
2:55 Definition of Receiver Operating Characteristics (ROC) Area Under the Curve (AUC)
4:27 Definition of Cut-off (Threshold)
5:25 A useful diagnostic test, balancing AUC and Cut-off
6:05 Definition of negative and positive predictive value (NPV and PPV)
7:25 Summary